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    GlossaryU2HR Mutation

    genetic alteration affecting hair growth regulation, potentially causing alopecia

    The U2HR mutation refers to a specific genetic alteration in the U2HR (U2 Hairless Repressor) gene, which is involved in the regulation of hair growth. This mutation can disrupt normal hair follicle function, potentially leading to conditions like alopecia, where hair loss occurs. For professionals, it's important to note that the U2HR gene plays a role in the signaling pathways that control hair follicle cycling and differentiation.

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      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 6 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community Ru58841 made my hair worse

      in General  138 upvotes 11 months ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community Ru delivery and heat outside .

      in Treatment  1 upvotes 9 months ago
      The conversation discusses concerns about the effectiveness of RU58841 due to high temperatures during delivery. A user reassures that the heat will not affect its efficacy.