research The Mammalian Hairless Protein as a DNA Binding Phosphoprotein 6 citations , June 2016 in “Journal of cellular biochemistry” The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.
research Glioblastoma cells express crucial enzymes involved in androgen synthesis: 3β‐hydroxysteroid dehydrogenase, 17‐20α‐hydroxylase, 17β‐hydroxysteroid dehydrogenase and 5α‐reductase 5 citations , July 2021 in “Endocrinology, diabetes & metabolism” Glioblastoma cells can make androgens, which might help the tumor grow.
research Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines 11 citations , September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
research Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells 9 citations , March 2018 in “International journal of molecular sciences” Allopregnanolone changes gene expression in glioblastoma cells.
research Allopregnanolone promotes proliferation and differential gene expression in human glioblastoma cells 25 citations , January 2017 in “Steroids” Allopregnanolone increases growth and changes gene activity in human brain cancer cells.