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Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse

research Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse

36 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

research Vasoactive Intestinal Peptide Operates as a Negative Regulator of Human Hair Follicle Pigmentation Ex Vivo

September 2024 in “Journal of Investigative Dermatology”

VIP reduces hair pigmentation by decreasing melanin production.

research [Peptidergic innervation in the sinus hair follicles of several mammalian species].

7 citations , October 1992 in “PubMed”

Sinus hair follicles in mammals have different nerve fiber types with species-specific patterns, especially in cats.

research Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin

37 citations , March 2006 in “Regulatory Peptides”

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone

98 citations , December 2008 in “Journal of Investigative Dermatology”

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

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