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research Chloroquine and cinchonine affect rat vascular smooth muscle tonus through calcium channels – in silico and in vitro approaches

January 2024 in “Bratislavské lekárske listy/Bratislava medical journal”

Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.

Skin Morphogenesis by Coupling Biochemical-Bioelectric Signals: Calcium Oscillations Coordinate Dermal Cell Movement by Epidermis-Derived SHH Signaling During Feather Bud Orientation

research 918 Skin morphogenesis by coupling biochemical-bioelectric signals: Calcium oscillations coordinate dermal cell movement by epidermis-derived SHH signaling during feather bud orientation

April 2019 in “Journal of Investigative Dermatology”

Calcium signals and SHH guide the direction of feather growth in chicken skin.

research Root hair growth in Arabidopsis thaliana is directed by calcium and an endogenous polarity

200 citations , November 1997 in “Planta”

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

140 citations , February 2014 in “Neuron”

Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.

research The incidental pore: Ca_V1.2 and stem cell activation in quiescent hair follicles

3 citations , June 2013 in “Genes & development”

CaV1.2 helps activate hair follicle stem cells without calcium flux.

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community Minoxidil’s mechanism of action on blood pressure as a potassium channel opening molecule

in Research 83 upvotes 5 months ago

Minoxidil works by opening potassium channels, leading to reduced blood pressure and potential side effects like reflex tachycardia. It is used for hair growth and affects blood pressure at high doses.

community Hairline stable but diffuse thinning with topical fin+min

in Finasteride 237 upvotes 5 months ago

The user experienced stable hairline but diffuse thinning after switching from oral finasteride to a topical solution of minoxidil and finasteride. They are concerned about the effectiveness of the topical treatment and are considering other options due to a recent decline in hair density.

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