The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.
Minoxidil caused water retention and gastrointestinal issues for the user, which improved after stopping the medication. The user is now using finasteride and topical minoxidil, experiencing excessive urination and concerns about systemic absorption.
The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.
People discuss taking finasteride and dutasteride with various drinks, noting that water is common, while some avoid grapefruit juice. Opinions vary on whether the choice of beverage affects drug absorption.
Taking Propecia (finasteride) with olive oil is unnecessary because it is water-soluble and already has high bioavailability. Dutasteride tablets should be taken with something fatty like olive oil to improve absorption.