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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 801 resultslearn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
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learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
Research
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research Skin manifestations and biophysical changes following weight reduction induced by bariatric surgery: A 2‐year prospective study
Bariatric surgery improved many skin conditions in obese patients but caused hair loss in some and decreased facial oil and skin elasticity.
research SAT383 Case Study: Impact of Weight Reduction and Oral Contraceptive Pills on Hyperandrogenism
Losing weight and taking birth control pills can greatly improve severe male hormone excess in women with PCOS.
research Urticariform plaques: delayed hypersensitivity reaction type IV to enoxaparin
A woman had a delayed allergic reaction to the blood thinner enoxaparin, treated with a steroid cream.
research Recurrent pruritic polymorphic lesions associated with weight loss
A man with itchy skin lesions and weight loss was diagnosed with a rare skin condition linked to a pancreatic tumor.
research Swiss Practice Recommendations for the Management of Hidradenitis Suppurativa/Acne Inversa
Swiss experts recommend specific guidelines for diagnosing and treating hidradenitis suppurativa to improve patient care.
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5 / 1000+ resultscommunity How I treated side effects
The conversation discusses treating side effects of hair loss treatments. Recommendations include lifting heavy weights, reducing body fat, taking ZMA and D3 supplements, improving diet, taking DIM, reducing finasteride dosage, avoiding alcohol, drinking water, getting quality sleep, and not obsessing over side effects.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community 3 months transformation (Min+Fin+Derma Roller)
The conversation is about a user's 3-month hair loss treatment using topical minoxidil, oral finasteride, a derma roller, ketoconazole shampoo, rosemary oil, and vitamin D supplements, alongside weight loss. Users discuss shedding, vitamin D benefits, and reducing sugar intake.
community Women's Reactions
Balding can make dating more challenging, especially with superficial attitudes, but confidence and fitness can help. Some embrace shaving their heads, while others focus on self-improvement and acceptance.
community I have been gaining weight easily since taking Dutasteride.
A user's experience of gaining weight while taking Dutasteride, and suggestions on how to continue using it without the negative side effects, such as exercising and tracking calories or switching to Finasteride.