Search

for
Search:

GlossaryAutoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (Whitaker Syndrome)

rare genetic disorder causing multiple endocrine issues, chronic fungal infections, and skin abnormalities

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy (APECED), also known as Autoimmune Polyendocrine Syndrome Type 1 (APS-1), is a rare genetic disorder characterized by the dysfunction of multiple endocrine glands, chronic mucocutaneous candidiasis (persistent fungal infections of the skin, nails, and mucous membranes), and ectodermal dystrophy (abnormalities in the skin, teeth, and nails). It is caused by mutations in the AIRE gene, which plays a crucial role in immune system regulation, leading to the body's immune system attacking its own tissues.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 380 results

research Whitaker syndrome: A case report of autoimmune polyendocrine syndrome type 1 with dilated cardiomyopathy

September 2024 in “Clinical Case Reports”

Early recognition and multidisciplinary management of Whitaker syndrome can improve patient outcomes.

research Hypoparathyroidism as the Single Major Component for Decades of Autoimmune Polyglandular Syndrome Type 1

2 citations , December 2020 in “Endocrinology, diabetes & metabolism case reports”

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

research Polyglandular Syndrome Type 1 Complicated with Dilated Cardiomyopathy: A Case Report

April 2024 in “Research Square (Research Square)”

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

research Polycystic Ovary Syndrome: Overview and Treatment

10 citations , November 2010 in “Journal of Pharmacy Practice”

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

research The Metabolic Syndrome in Children and Adolescents

19 citations , January 2005 in “Paediatrics and Child Health”

Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.

View more "whitaker syndrome" in research →

Community Join

1 / 1 results

community 22 | ~34 Months Finasteride Update

in Progress Pictures 818 upvotes 1 year ago

A user shared their 34-month update on using finasteride for hair loss, noting they maintained regrowth even after stopping minoxidil a year ago. Other users shared similar experiences and expressed admiration for the results.