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research Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes

1 citations , November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

research The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches

42 citations , May 2016 in “Annual Review of Cell and Developmental Biology”

Fat cells are important for tissue repair and stem cell support in various body parts.

Knockout of mTOR/Akt Inhibitor REDD1 Results in Hair Cycle-Independent Dermal Adipose Expansion by Promoting Adipocyte Differentiation

research 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation

April 2019 in “Journal of Investigative Dermatology”

Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.

research Defining dermal adipose tissue

218 citations , May 2014 in “Experimental Dermatology”

Skin fat cells help with skin balance, hair growth, and healing wounds.

research The Role of Immature and Mature Adipocytes in Hair Cycling

30 citations , December 2018 in “Trends in Endocrinology and Metabolism”

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Fats on your Head to Stop Hair Loss?

in Research/Science 140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Adipocyte lipolysis activates epithelial stem cells for hair regeneration through fatty acid metabolic signaling

in Research/Science 22 upvotes 8 months ago

Fatty acid metabolic signaling can activate epithelial stem cells for hair regeneration. Oleic and palmitoleic acids showed the best results, but practical application on humans remains uncertain.

community The Big Fat Layer II

in Research/Science 26 upvotes 5 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 84 upvotes 2 years ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

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