research Wnt signaling induces epithelial differentiation during cutaneous wound healing 66 citations , July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
research Fondation René Touraine September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling 59 citations , April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
research Stem cell plasticity enables hair regeneration following Lgr5+ cell loss 56 citations , May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
research Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche 133 citations , September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
learn KY19382 compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles
learn Osteopontin signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss