Concerns about CosmeRNA safety mechanisms
Treatment 4/13/2023

At a glance

In this question or advice post, the primary subjects mentioned are

💧 CosmeRNA (topical)

💊 Finasteride (oral)

💧 Minoxidil (topical) 5%

the tone is 😞 negative.

Other terms

Fluridil nanoparticle specificity siRNA stability SAMiRNA topical application clinical trials FDA approval Alpecin shampoo androgenic alopecia AR systemic absorption nanoparticles siRNA topical FDA Alpecin Rogaine androgen receptor systemic

Concerns about CosmeRNA safety mechanisms and potential side effects. Discussion includes comparisons to Fluridil and questions about nanoparticle specificity and siRNA stability.

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5 / 188 results

community Is there a 50 year old "young old man" here who started oral fina at 0.1 mg to maintain his hair?

in Finasteride/Dutasteride 2 upvotes 2 years ago

A person experienced side effects from topical finasteride and is now trying a low dose of oral finasteride (0.1mg) for hair maintenance, alongside topical minoxidil, Fluridil, CosmeRNA, and exosomes. They are also taking resveratrol and nettle leaf to mitigate side effects.

community Does anybody else have non-fin/min stacks that they feel are working?

in Progress Pictures 7 upvotes 2 years ago

The user is discussing their hair loss treatment stack, which includes CB-03-01, Fluridil, Alfatradiol, Cosmerna, microneedling, and Stemoxydine. They have seen some new hair growth but wish they could use finasteride.

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The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.

community Hold up... CosmeRNA/SAMiRNA is actually coming real soon?

in Technology 31 upvotes 3 years ago

A user discovered CosmeRNA, a new hair loss treatment with clinical research backing, set to release soon. The conversation revolves around its potential effectiveness, cost, and how it compares to existing treatments like Minoxidil and Finasteride, with some users expressing hope for a side-effect-free option.

Related Research

2 / 2 results

Efficacy of Cosmerna ARI in Improving Androgenetic Alopecia in Europeans: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial Over 6 Months

research Efficacy of Cosmerna ARI in Improving Androgenetic Alopecia in Europeans: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial over 6 months

December 2025 in “Clinical & Experimental Dermatology and Therapies”

Cosmerna ARI effectively reduces hair loss and increases hair density in Europeans with androgenetic alopecia.

research Weekly treatment with SAMiRNA targeting the androgen receptor ameliorates androgenetic alopecia

3 citations , January 2022 in “Scientific Reports”

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.