July 2025 in “Journal of Investigative Dermatology” November 2025 in “Journal of Investigative Dermatology” Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” The study establishes a high-resolution, multimodal atlas of the human scalp by integrating spatial transcriptomics with single-cell RNA-seq and multiomics data. This atlas reveals spatially organized epithelial and mesenchymal states, linking transcriptional programs to chromatin dynamics and lineage trajectories at single-cell resolution. It uncovers human-specific tissue organization principles and new features of hair follicle architecture. The atlas is used to project patient scRNA-seq profiles from alopecia areata and lichen planopilaris, identifying disease-specific perturbations in fibroblasts, epithelial, and immune populations. This work delineates cellular programs associated with non-scarring versus scarring hair loss, highlighting pathways with diagnostic and therapeutic potential, and provides a foundational resource for human hair biology.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.
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December 2022 in “Scientific Data” The study maps how genes are regulated during mouse hair growth.