Adult Female Acne: Clinical Characteristics and Factors Significantly Associated with Polycystic Ovary Syndrome

    August 2021 in “ Australasian Journal of Dermatology ”
    Pattriya Chanyachailert, Leena Chularojanamontri, Panicha Chantrapanichkul, Papapit Tuchinda, Thanyarat Wongwananuruk, Phatcharee Sardod, Kanokvalai Kulthanan
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    TLDR Acne in adult women is often linked to polycystic ovary syndrome, especially in those who are younger, have premenstrual acne flare-ups, and irregular periods.
    The study "Adult female acne: Clinical characteristics and factors significantly associated with polycystic ovary syndrome" investigated the clinical characteristics of adult female acne (AFA) and its association with polycystic ovary syndrome (PCOS). The study involved 208 patients aged 25 years or older, with a mean age of 31.8 years. The results showed that 47.1% had persistent acne, 26.9% had late-onset acne, and 26% had recurrent acne. Common factors that aggravated acne included pre-menstruation (72.6%) and stress (53.8%). A higher body mass index (BMI) was positively correlated with acne severity. PCOS was identified in 48.1% of the patients. Factors associated with PCOS included younger age (≥25 to <33 years), premenstrual flare, and irregular menstruation. The study concluded that persistent acne with moderate severity was common in AFA patients and higher BMI was associated with acne severity. PCOS should be screened in AFA patients with younger age, premenstrual flare, and irregular menstruation.
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