Advances in Clinical Applications of Microneedle

    June 2025 in “ Frontiers in Pharmacology ”
    Kequan Chen, Xinyu Sun, Y. Liu, Shiyu Li, Dianhuai Meng
    TLDR Microneedles improve drug delivery, patient compliance, and have potential in cancer treatment and skin care.
    Microneedle (MN) technology has shown significant advancements in clinical applications by effectively penetrating the skin barrier to enhance transdermal drug delivery and biosignal detection. MNs improve drug delivery efficiency, patient compliance, and reduce side effects. They also enable sensitive real-time biomarker monitoring when combined with biosensors. In cancer treatment, MNs offer potential for targeted drug delivery, gene therapy, and immunostimulation. Additionally, MNs have promising applications in wound healing, scar repair, anti-aging, and skin disease treatment. This review highlights recent progress in these areas and discusses future development prospects.
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