Alopecia Areata–Specific Patient-Reported Outcome Measures

March 2025 in “ JAMA Dermatology ”

Emadodin Darchini‐Maragheh, Anthony Moussa, Nicole Kah Mun Yoong, Laita Bokhari, Leslie N. Jones, Rodney Sinclair

alopecia areata patient-reported outcome measures PROMs Alopecia Areata Patient Priority Outcomes AAPPO health-related quality of life symptom-based measures psychometric testing AA-specific PROMs

TLDR High-quality validation studies are needed to improve alopecia areata patient-reported outcome measures.

This systematic review evaluated the quality of alopecia areata-specific patient-reported outcome measures (PROMs) and identified a need for high-quality validation studies on their internal structure. The review analyzed 15 articles, including 8 developmental and 7 validation studies, covering 11 PROMs. Three PROMs focused on health-related quality of life, five were symptom-based, and three combined constructs. The Alopecia Areata Patient Priority Outcomes (AAPPO) was highlighted for its high-quality evidence of structural validity, internal consistency, and test-retest reliability. However, no study reported measurement error. The review emphasizes the importance of rigorous psychometric testing to improve the quality of AA-specific PROMs.

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6 / 6 results

research Beyond Health-Related Quality of Life: Initial Psychometric Validation of a New Scale for Addressing the Gap in Assessing the Full Range of Alopecia Areata Psychosocial Burden

8 citations , June 2023 in “British Journal of Dermatology”

The SAAD-41 scale effectively measures the psychosocial impact of alopecia areata.

research Validation of the Alopecia Areata Patient Priority Outcomes Questionnaire in Adults and Adolescents with Alopecia Areata

22 citations , November 2021 in “Dermatology and Therapy”

The AAPPO questionnaire is a reliable tool for assessing hair loss impact in alopecia areata patients.

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11 citations , March 2021 in “Dermatology and therapy”

Researchers created a new tool to measure the effects of alopecia areata from the patient's view, focusing on hair loss, daily life, and emotional health.

Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clinical Outcome Assessments in Japan

research Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clinical Outcome Assessments in Japan

7 citations , January 2021 in “Dermatology and therapy”

Both dermatologists and patients in Japan agree that treatment success for alopecia areata is having 20% or less scalp hair loss.

‘You Lose Your Hair, What’s the Big Deal?’ I Was So Embarrassed, I Was So Self-Conscious, I Was So Depressed: A Qualitative Interview Study to Understand the Psychosocial Burden of Alopecia Areata

research ‘You Lose Your Hair, What’s the Big Deal?’ I Was So Embarrassed, I Was So Self-Conscious, I Was So Depressed: A Qualitative Interview Study to Understand the Psychosocial Burden of Alopecia Areata

30 citations , September 2020 in “Journal of Patient-Reported Outcomes”

Alopecia Areata (AA) causes significant emotional distress, including feelings of embarrassment, depression, and anxiety, and impacts social interactions and daily activities.

Development of Clinician-Reported Outcome and Patient-Reported Outcome Measures for Eyebrow, Eyelash, and Nail Assessment in Alopecia Areata

research Development of Clinician-Reported Outcome and Patient-Reported Outcome Measures for Eyebrow, Eyelash, and Nail Assessment in Alopecia Areata

56 citations , August 2020 in “American Journal of Clinical Dermatology”

New tools help assess eyebrow, eyelash, and nail changes in Alopecia Areata, improving understanding of patient experiences.