Hair And Nail Conditions: Alopecia Management

June 2022 in “ PubMed ”

Amy Fox

alopecia nonscarring alopecia scarring alopecia hair loss hair density topical drugs oral drugs intralesional injections hair transplantation

TLDR Alopecia treatment takes time, needs specific plans, and may include drugs or hair transplants.

The document discussed the management of nonscarring and scarring alopecias, focusing on stabilizing hair loss and improving hair density. Management was often a lengthy process, requiring months to years, and could involve addressing multiple causes of alopecia. Treatment goals were diagnosis-specific, and physicians were advised to set realistic expectations for hair regrowth. Patients were counseled on hair care practices, personal care products, vitamins, and hairstyling devices. Management options included topical and oral drugs, intralesional injections, and potentially hair transplantation for select patients. There were more evidence-based guidelines for nonscarring alopecias compared to scarring alopecias, due to the rarity of the latter and the lack of large data sets for guideline development.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community How is there still no consensus on Topical Dutasteride in 2024?

in Finasteride/Dutasteride 147 upvotes 1 year ago

The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

community Am I missing something with pp405?

in Research/Science 32 upvotes 11 months ago

PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

community Topical Minoxidil is a pain in the ass for diffuse thinners

in Minoxidil 95 upvotes 2 years ago

Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

community Quote from Pelage (PP-405) Spokesperson...

in Research/Science 121 upvotes 2 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.