Variations in Alanine Aminotransferase Levels Within the Normal Range Predict Metabolic and Androgenic Phenotypes in Women of Reproductive Age

    October 2010 in “ Scandinavian Journal of Clinical & Laboratory Investigation ”
    Olusegun A. Mojiminiyi, Fatma H. Safar, Hazem Al Rumaih, Michael Diejomaoh
    Image of study
    TLDR Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.
    In the 2010 study involving 200 women aged 18-48, including those with polycystic ovary syndrome (PCOS) and idiopathic hyperandrogenism, it was found that variations in alanine aminotransferase (ALT) levels within the normal range are linked to metabolic and androgenic phenotypes. ALT levels correlated positively with various metabolic and androgenic markers and inversely with factors indicating insulin sensitivity. These correlations were not dependent on obesity. An ALT level of ≥ 18 IU/L was significantly associated with PCOS. The study concluded that normal-range ALT levels could indicate metabolic and androgenic abnormalities in women of reproductive age and suggested that ALT could be used beyond liver disease diagnosis to identify women at risk for conditions like PCOS and insulin resistance.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 7 results

      community concerns about starting minoxidil

      in Female  1 upvotes 4 years ago
      An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.

      community Testosterone, gray hair, low vitamin D, and switching to oral Minoxidil

      in Treatment  4 upvotes 5 years ago
      A woman experiencing hair loss due to high testosterone and low vitamin D is using treatments like Dutasteride, Rogaine, zinc, ketoconazole shampoo, dermastamp, iRestore, multivitamins, scalp massager, and vitamin D. She plans to switch to oral Minoxidil under medical supervision.

      community 11 Months Topical Fin 0.3%+Min 6% daily, Last 2 Months Added Min 5% Foam at Night, Late 30s Male Progress

      in Progress Pictures  186 upvotes 2 years ago
      The user "_Mad_Jack_" shared their progress pictures of using topical finasteride and minoxidil for 11 months. They experienced good hair retention and increased overall hair count, but no regrowth of the hairline. They are considering switching to oral finasteride and microneedling for better results. Testicular pain was a side effect experienced during the treatment. Another user mentioned getting a hair transplant to cover their crown.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 2 weeks ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

    Similar Research

    5 / 1000+ results