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    GlossaryIdiopathic Hyperandrogenism

    excessive male hormone production without known cause

    Idiopathic Hyperandrogenism refers to a condition where there is an excessive production of androgens (male hormones) in the body without a known cause. This can lead to symptoms such as excessive hair growth, acne, and irregular menstrual cycles in women. The term "idiopathic" means that the exact cause of the hormone imbalance is unknown, distinguishing it from hyperandrogenism caused by identifiable conditions like polycystic ovary syndrome (PCOS) or adrenal gland disorders.

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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

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      community I wish I were a man so bad. Life is cruel

      in Female  223 upvotes 4 weeks ago
      A woman with androgenetic alopecia uses Dutasteride and Bicalutamide but feels devastated due to increased sensitivity to DHT. She considers wigs, Minoxidil, and seeks advice on options like spironolactone, hair transplants, and therapy.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community AA and Hirsutism but T levels are normal

      in Female  6 upvotes 5 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 2 years ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  8 upvotes 2 years ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.