Health Consequences of Anabolic Steroids: A Sexual-Medicine Perspective
April 2026
in “
International Journal of Impotence Research
”
anabolic-androgenic steroids AAS hypothalamo-pituitary-gonadal axis hypogonadism libido erectile dysfunction gynecomastia spermatogenesis cardiovascular risks hepatic risks hematologic risks tendon risks neuropsychiatric risks dermatologic risks steroids testosterone hormonal imbalance sexual dysfunction breast enlargement sperm production heart risks liver risks blood risks skin risks
TLDR Anabolic steroid abuse can cause sexual, fertility, and health problems.
Nonmedical use of anabolic-androgenic steroids (AAS) is increasingly seen in sexual medicine, often presenting with sexual or fertility issues. AAS abuse can suppress the hypothalamo-pituitary-gonadal axis, causing hypogonadism, reduced libido, erectile dysfunction, gynecomastia, and impaired spermatogenesis. Recovery after stopping AAS varies, with hormonal balance often returning before semen quality, and prolonged/high-dose use can delay or hinder recovery. AAS use also raises cardiovascular, hepatic, hematologic, tendon, neuropsychiatric, and dermatologic risks, influenced by dose and duration. Without robust trials, management should focus on stopping AAS use, preventing relapse, and tailoring follow-up based on individual needs, with pharmacological recovery induction used selectively.