The Antioxidant Activities and Hair-Growth Promotion Effects of Tenebrio Molitor Larvae Extracts

November 2017 in “ JoLS Journal of Life Sciences ”

백민희, 서민철, 김미애, Eun‐Young Yun, Jae‐Sam Hwang

Tenebrio molitor larvae extracts antioxidant activities DPPH radical scavenging nitrite scavenging human dermal papilla cells DPCs NIH3T3 fibroblast cells DHT cytotoxicity potassium channel blocking tolbutamide TMEs dermal papilla cells fibroblast cells

TLDR Tenebrio molitor larvae extracts may help prevent hair loss and promote hair growth.

The study investigated the antioxidant activities and hair-growth promotion effects of Tenebrio molitor larvae extracts (TMEs). The extracts demonstrated significant antioxidant activities, with DPPH radical scavenging at 81.17% and nitrite scavenging at 43.69%, comparable to blueberry extracts. TMEs promoted the proliferation of human dermal papilla cells (DPCs) and NIH3T3 fibroblast cells, increasing cell proliferation by 218% and 116%, respectively. Additionally, TMEs prevented DHT-induced cytotoxicity in DPCs and countered the potassium channel blocking effects of tolbutamide in NIH3T3 cells. These findings suggested that TMEs could serve as a functional therapeutic agent for preventing hair loss and promoting hair growth.

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