Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) in a 56-Year-Old Patient With Silicone Breast Implants: A Case Report

    May 2026 in “ Cureus ”
    Victor Hugo Garzón Ortega, Jesús C Ceballos Villalva, Fernando Fernández Varela Gómez, Jaime Enrique Flores Avila, Hernando Alberto Vázquez Sánchez, Alec Anceno Olivares, Daniela Téllez-Palacios
    TLDR Removing silicone breast implants may improve symptoms of autoimmune/inflammatory syndrome.
    This case report discusses a 56-year-old woman who developed autoimmune/inflammatory syndrome induced by adjuvants (ASIA) following silicone breast implant exchange, presenting with symptoms such as muscle weakness, edema, alopecia, and elevated creatine kinase levels. Despite initial immunosuppressive treatment, her symptoms persisted, leading to the decision to remove the implants and perform mastopexy. The case emphasizes the importance of a multidisciplinary approach and suggests that explantation may improve outcomes for patients with ASIA related to silicone implants.
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