Bioactive Inorganic Particles-Based Biomaterials for Skin Tissue Engineering

This review discussed the development of bioactive inorganic particles-based biomaterials for skin tissue engineering, addressing the urgent clinical need for effective treatments for severe cutaneous wounds. It outlined the evolution of these biomaterials through three stages: single inorganic materials, inorganic/organic composite materials, and inorganic particles-based cell-encapsulated living systems. The review described the primary types of bioactive inorganic biomaterials and cited recent representative studies. It also explored approaches to constructing composite material systems incorporating inorganic components for wound healing. The review concluded with suggestions for future directions in developing novel bioactive inorganic particles-based biomaterials for skin regeneration.