Biological Properties of Polycaprolactone and Barium Titanate Composite in Biomedical Applications

The review examines the potential of polycaprolactone (PCL) and barium titanate (BT) composites in biomedical applications, focusing on their mechanical, piezoelectric, and biological properties that enhance osseointegration and healing processes. PCL is a biodegradable polymer, while BT is a piezoelectric ceramic, both contributing to improved tissue engineering outcomes. The composites show promise in antibacterial activity, cytotoxicity, and osseointegration, with modifications like incorporating silver or essential oils enhancing antibacterial properties. However, challenges remain, such as optimizing BT concentration and improving PCL's hydrophilicity and cell adhesion. The review underscores the need for further research to optimize these composites for specific applications, including dental implants and coatings.