Evaluation of Changes in Blood Parameters and Clinical Symptoms in Dogs With Adrenal Dysfunction

    Jannika Rettig
    TLDR Clinical signs and blood tests are not very helpful in diagnosing hyperadrenocorticism in dogs.
    A retrospective study of 17 dogs with hyperadrenocorticism in Elversberg, Germany, aimed to explore clinical symptoms and blood parameters associated with the disease. Common symptoms included polyuria, polydipsia, lethargy, alopecia, and excessive panting. Blood analysis revealed eosinopenia, thrombocytosis, and elevated levels of alkaline phosphatase and alanine aminotransferase. A moderate positive correlation was found between alanine aminotransferase and alkaline phosphatase, and a significant negative correlation between glucose and sodium. No significant differences were observed in blood parameters between male and female dogs, nor was there a significant correlation between test results and blood parameters. The study concluded that clinical signs and blood parameters do not significantly aid in diagnosing hyperadrenocorticism.
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