Optimizing Burn Injury Care: A Comparative Network Meta-Analysis of Skin Grafts' Efficacy

    February 2025 in “ Jurnal Kedokteran Brawijaya ”
    Imke Maria Del Rosario Puling, Nyoman Deva Pramana Giri, Teresa Almadita, Jane Limantara, Arviansyah Arviansyah
    TLDR Autologous skin cell transplantation speeds up healing and xenografts improve skin color in burn care.
    This study evaluated the efficacy of different skin grafts in burn injury healing, focusing on reepithelialization time and repigmentation rate. A meta-analysis of 7 articles, mostly low-risk bias, revealed that device-facilitated autologous skin cell transplantation significantly increased reepithelialization rates, while xenografts showed the highest repigmentation rate at 87.50%. Despite xenografts' effectiveness in wound healing, the promising results of autologous skin cell transplantation suggest its potential for clinical use due to its outstanding efficacy and minimal repigmentation.
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