TLDR Caffeine can boost health but may cause side effects like high blood pressure and migraines.
The document reviews the effects of caffeine on human health, highlighting its potential benefits and risks. Caffeine is known for enhancing athletic performance, stimulating the central nervous system, and improving mood and alertness. While moderate consumption (up to 400 mg daily) is generally safe, excessive intake can lead to adverse effects such as anxiety and insomnia. The review discusses caffeine's potential anticancer, immunological, anti-inflammatory, cardiovascular, and neurological protective effects. Emerging strategies for caffeine delivery, including encapsulation, are explored to enhance its biological activities. The document emphasizes caution for certain populations, such as adolescents, pregnant women, and individuals with health issues. Additionally, caffeine's ability to inhibit 5-α-reductase and increase blood supply to hair follicles makes it beneficial for alopecia treatment, with liposomes co-encapsulating minoxidil and caffeine significantly increasing hair weight.
18 citations
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May 2023 in “Preprints.org” Caffeine can boost health but may cause side effects like high blood pressure and migraines.
10 citations
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July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
8 citations
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January 2020 in “Skin Pharmacology and Physiology” Caffeine improves hair growth, thickness, and reduces shedding.
35 citations
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January 2018 in “Skin pharmacology and physiology” Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
32 citations
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December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
August 2024 in “Cosmetics” Caffeine is beneficial for skin and hair treatments but needs better delivery methods to penetrate deeper skin layers.
153 citations
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October 2012 in “Skin Pharmacology and Physiology” Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
27 citations
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August 2018 in “Therapeutic Delivery” Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.
13 citations
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September 2023 in “Molecules” Liposomal coffee berry extract improves skin elasticity and reduces melanin better than regular extract.
43 citations
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July 2023 in “Pharmaceuticals” Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.