Could the Risk of Chronic Degenerative Valve Disease in Dogs Depend on Exposure to Endocrine-Disrupting Chemicals Polluting the Environment?

    November 2025 in “ Animals
    Krystyna Makowska, Julia Martı́n, Robert Pasławski, Andrzej Rychlik, Irene Aparicio, Juan Luís Santos, Esteban Alonso, Małgorzata Górecka-Politańska, Sławomir Gonkowski
    TLDR Exposure to certain chemicals may increase the risk of heart disease in dogs.
    The study explored the potential link between exposure to endocrine-disrupting chemicals (EDCs) and chronic degenerative valve disease (CDVD) in dogs by analyzing hair samples from 60 dogs, half of which had CDVD. Results indicated that dogs with CDVD had significantly higher concentrations of certain EDCs, such as methylparaben, ethylparaben, propylparaben, perfluoroheptanoic acid, and perfluorooctanoic acid, compared to healthy dogs. Although no significant differences were found for bisphenol A (BPA) and benzophenone-3 (BP-3), dogs with CDVD had approximately twice the concentration levels of these chemicals. The study suggests a possible association between EDC exposure and increased CDVD risk, emphasizing the need for further research to confirm these findings and understand the impact of EDCs on canine heart health.
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