Evolution of Cell Therapies Derived from Adipose Tissue: Historical Perspectives, Current Development Trends and Future Directions

    August 2025 in “ Biology Direct
    S. Gandolfi, Élise Lupon, Audrey Varin, Agnès Coste, Brigitte Sallerin, C. Boyer, Yanis Berkane, B. Chaput
    TLDR Adipose tissue therapies have advanced from tissue to cell and cell-free treatments, showing promise but also limitations.
    Adipose tissue has gained significant attention in regenerative medicine due to its regenerative, anti-inflammatory, and pro-angiogenic properties. The field has evolved from tissue transfer to cell transfer, and now to cell-free derivatives and bioengineering applications. This evolution aids in identifying potential therapeutic products and indications while also highlighting the limitations and future directions of adipose tissue-based therapies.
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