The Effectiveness of Cerium Oxide Nanoparticle-Based Drugs in Wound Healing in Animal Models

    November 2025 in “ Molecules ”
    A.G. Erokhina, Maria Petrovna Kruglova, Victor Stupin, А.В. Царегородцев, В. А. Парфенов, Н.Е. Мантурова, Ekaterina Silina
    TLDR Cerium oxide nanoparticles may help wounds heal faster, but more research is needed.
    Cerium oxide nanoparticles (CeO2 NPs) show promise in wound healing due to their regenerative properties, including antioxidant effects and stimulation of cell activity. A review of 25 in vivo studies highlights their potential in accelerating wound closure and modulating tissue repair phases in animal models. However, the effectiveness of these nanoparticles depends on synthesis methods and formulation components. While promising for clinical use, standardized synthesis protocols and rigorous comparative studies are needed to ensure reliable therapeutic applications.
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