Additive Effects of Clove (Syzygium Aromaticum) and Rosemary (Rosmarinus Officinalis) Essential Oils on Hair Regrowth in a Rat Model: A Comparative Study with 2% Minoxidil

The study examined the effects of clove and rosemary essential oils on hair regrowth in a rat model, comparing them to 2% minoxidil. Thirty male Wistar rats were divided into groups receiving different treatments for 35 days. All active treatments significantly improved hair regrowth, with the mixture of oils outperforming minoxidil. The mixture led to faster hair regrowth initiation (6.5 days) and completion (21.83 days), as well as greater hair weight (22.2 mg/cm²) and length (16.67 mm). Histological analysis showed higher follicle density in treated groups. The study concluded that the combination of these essential oils had an additive effect, surpassing minoxidil in promoting hair regrowth.