Crystalluria With Sulphadiazine

The document reported a case of acute ureteric obstruction in a young female experiencing her first presentation of recurrent ocular toxoplasmosis. The treatment for ocular toxoplasmosis typically involved the use of sulphadiazine and pyrimethamine, which are synergistic antagonists of folate metabolism, along with folinic acid to prevent bone marrow suppression. Steroids were also commonly used in combination with antimicrobials for sight-threatening inflammatory infections. The case highlighted the occurrence of crystalluria, a condition where crystals form in the urine, associated with the use of sulphadiazine.