TLDR Cyclosporin and minoxidil promote hair growth.
The study investigated the effects of cyclosporin, minoxidil, testosterone, estradiol, and corticosteroids on hair growth in nude mice. It was found that cyclosporin and minoxidil had hair growth-stimulating effects, while the roles of testosterone, estradiol, and corticosteroids were less clear. The research contributed to understanding the potential of these compounds in promoting hair growth, although the specific mechanisms and efficacy varied among the substances tested.
10 citations
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July 1994 in “Journal of Dermatological Science” Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.
13 citations
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June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
151 citations
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July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
81 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
38 citations
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June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
