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GlossaryCyclosporine

immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

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research The Use of Cyclosporine in Dermatology: Part I

131 citations , November 2010 in “Journal of the American Academy of Dermatology”

Cyclosporine is effective for skin conditions but has declined in use due to toxicity concerns.

research A Murine Model for Inducing and Manipulating Hair Follicle Regression: Effects of Dexamethasone and Cyclosporin A

124 citations , August 1994 in “Journal of Investigative Dermatology”

Dexamethasone speeds up hair loss in mice, while cyclosporin A slows it down.

research Toxicity of the Immune Suppressant Cyclosporin A in the Rat

116 citations , October 1982 in “The Journal of Pathology”

Cyclosporin A is highly toxic to rats, causing severe health issues and death.

research Cyclosporin A: A New Drug in the Field of Canine Dermatology

84 citations , March 2004 in “Veterinary Dermatology”

Cyclosporin is effective in treating dog skin diseases and has fewer side effects compared to other treatments.

research Topical Cyclosporine in Alopecia Areata

69 citations , February 1987 in “Archives of Dermatology”

Topical cyclosporine lotion led to hair regrowth in a man with alopecia universalis.

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community how to compound topical cyclosporine

in Treatment 9 upvotes 3 years ago

The conversation is about compounding topical cyclosporine for hair loss, suggesting it needs an oil base like castor oil. The user seeks tips or tricks for the process.

community What happened to the 40mg dutasteride daily and Cyclosporine dude?

in Chat 40 upvotes 6 months ago

A user previously claimed to take 40mg of dutasteride daily and planned to try Cyclosporine, but their account and comments have since been deleted, raising concerns about their well-being. Other users discussed the risks and effectiveness of high doses of dutasteride, with some sharing their own experiences using dutasteride, finasteride, and minoxidil for hair loss treatment.

community Forgotten 'Total Revival' Stack

in Research/Science 42 upvotes 8 months ago

Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

community RT1640 - Gray Hair Reversal Recipe

in Research/Science 3 upvotes 3 years ago

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 10 months ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

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