A Retrospective Study on the Use of Dermis Micrografts in Platelet-Rich Fibrin for the Resurfacing of Massive and Chronic Full-Thickness Burns

    September 2019 in “ Stem Cells International ”
    Alessandro Andreone, Daan den Hollander
    TLDR The PRF/micrograft spray-on skin method effectively healed massive and chronic burns quickly.
    This retrospective study investigated the use of autologous micrografts combined with platelet-rich fibrin (PRF) for treating massive and chronic full-thickness burns in five male patients. The technique involved applying a solution of micrografts and PRF to the wound bed, followed by meshed skin grafting. The study found high graft take rates (96%-98%) and successful wound healing, with complete reepithelialization occurring within days. The approach showed potential as an effective treatment, particularly in resource-limited settings, although the small sample size and retrospective design indicated the need for further randomized trials to confirm efficacy.
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