29 citations
,
September 2019 in “Stem Cells International” The PRF/micrograft spray-on skin method effectively healed massive and chronic burns quickly.
25 citations
,
May 2014 in “Facial Plastic Surgery” PRFM may help treat hair loss, especially in mild cases.
23 citations
,
December 2021 in “International Journal of Environmental Research and Public Health” A-PRF reduces pain and complications after wisdom tooth removal.
11 citations
,
August 2025 in “Journal of Periodontal Research” Over the past 30 years, autologous platelet concentrates (APCs) like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have been developed to enhance healing by concentrating growth factors and cells. PRF, which eliminates anti-coagulants, has shown superior natural healing benefits, particularly in dentistry for procedures such as periodontal regeneration and sinus grafting. Beyond dental applications, PRF is effective in treating diabetic ulcers, joint pain, and in esthetic medicine. Recent advancements include horizontal centrifugation techniques and the development of extended-PRF (e-PRF) membranes, which extend membrane degradation up to 4 months, offering a new alternative to collagen membranes in dental procedures.
4 citations
,
October 2024 in “BMC Oral Health” Platelet-rich fibrin shows promise for treating oral lesions but needs more research.