Dual-Action Regenerative Therapies: Regeneration and Antimicrobial Effects of Platelet- and Marrow-Derived Biologics

This review discusses the dual regenerative and antimicrobial properties of platelet- and marrow-derived biologics, such as PRP and BMAC, which are used in tissue repair and regeneration. These biologics promote healing and reduce infection risk through growth factors, cytokines, and cellular components. They show significant regenerative effects in musculoskeletal conditions, wound healing, and cartilage repair. However, clinical outcomes are affected by preparation methods, patient factors, and lack of standardization. Despite their potential to reduce reliance on pain medications and improve function, these therapies face challenges like inconsistent protocols, limited long-term safety data, and regulatory issues. The review emphasizes the need for standardized procedures and further research to optimize their clinical use in pain medicine.