Dupilumab Associated Progression of Alopecia Areata to Alopecia Universalis: A Case Report

    January 2026
    Abrar Alameri
    TLDR Dupilumab may worsen hair loss in patients with alopecia areata.
    This case report discusses the progression of alopecia areata to alopecia universalis in a patient treated with dupilumab. The report highlights a potential adverse effect of dupilumab, a medication typically used for treating atopic dermatitis, which may contribute to the worsening of hair loss conditions. The case emphasizes the need for clinicians to be aware of this possible side effect when prescribing dupilumab to patients with pre-existing alopecia areata. Further research is suggested to understand the mechanisms behind this progression and to evaluate the risk factors involved.
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