Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model

    February 2022 in “ Biological Trace Element Research ”
    Betül Demir, Demet Çiçek, Cemal Orhan, Beşir Er, Füsun Erten, Mehmet Tuzcu, İbrahim Hanifi Ozercan, Nurhan Şahin, James Komorowski, Sara Perez Ojalvo, Sarah Sylla, Kazım Şahin
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    TLDR The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
    The study involved 28 rats and examined the effects of Arginine Silicate Inositol Complex (ASI) and a novel form of Biotin (MgB) on hair and nail growth. The results showed that the combination of ASI and MgB significantly increased hair density and the percentage of hair in the growth phase, while decreasing the percentage of hair in the resting phase. The group receiving the highest dose of MgB showed a 55% increase in hair density and a 48.66% increase in the growth phase. This group also showed significant nail growth. Molecular analysis revealed increased levels of growth factors and signals crucial for hair follicle formation and regeneration. The study concluded that the combination of ASI and MgB promotes hair and nail growth, potentially offering a new approach for treating conditions like alopecia.
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