Effects of Collagen Peptides on Gene Expression Related to Hair Cycle Activation in the Skin

The document investigated the effects of collagen peptides on gene expression related to hair cycle activation in mouse skin. It was found that oral administration of collagen hydrolysates induced the expression of genes associated with the hair cycle, molting cycle, epidermis development, and ectoderm development in mice. Additionally, the collagen dipeptide prolyl-hydroxyproline (Pro-Hyp) was shown to influence gene expression related to the hair cycle in a co-culture of mouse skin cells. These findings suggested that collagen peptides could potentially promote hair growth by activating specific genetic pathways in the skin.