Case-Control Study: The Effects of Synthetic Ceramide on Dandruff, Erythema, Sebum Secretion, and Water Loss of Scalp

    January 2019 in “ 프로그램북(구 초록집)
    Hye Ree Park, Dong Geon Lee, Ji Hee Jung, Jung Eun Kim, Hoon‐Chul Kang
    TLDR Synthetic ceramide improves dandruff, erythema, and reduces scalp water loss.
    This study evaluated the effects of synthetic ceramide on dandruff, erythema, sebum secretion, and water loss in a case-control study with 20 subjects. After 4 weeks of using a ceramide shampoo, 8 out of 10 patients in the ceramide group showed improvement in dandruff compared to 4 in the control group. For erythema, 4 patients in the ceramide group showed improvement compared to 3 in the control group. Although sebum secretion increased in the ceramide group and decreased in the control group, the change was not statistically significant. However, the water content of the scalp showed a tendency to increase in the ceramide group, while it significantly decreased in the control group. The study concluded that synthetic ceramide was effective in improving dandruff, erythema, and reducing water loss.
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