Electron Microscope Studies of the Human Epidermis: The Clear Cell of Masson (Dendritic Cell or Melanocyte)

This study used electron microscopy to examine the human epidermis, identifying a distinct dendritic cell similar to the melanocyte of the hair bulb. These cells, which can contain melanin, have larger and more numerous mitochondria and a more complex endoplasmic reticulum compared to other epidermal cells. They lack tonofilaments and do not form intercellular bridges. The study suggests these cells are identical to the dopa-positive, clear cell of Masson. Additionally, it was found that permanganate fixation better preserves membranous structures in the epidermis than osmium tetroxide fixation.