The Role Of Estrogen In Cutaneous Aging And Repair

The document explored the impact of estrogen, particularly 17β-estradiol, on skin aging and wound healing, noting that estrogen deficiency contributed to these issues, especially in post-menopausal women. Treatment with 17β-estradiol was effective in restoring normal healing and protecting against infections. It also suggested the potential of selective estrogen receptor modulators (SERMs) as future alternatives for clinical use. However, further molecular and mechanistic studies were necessary to develop new therapeutics targeting estrogen receptors to enhance skin health and repair.