Exosome-Based Therapies for Alopecia: A Systematic Review of Clinical Efficacy and Safety

Exosome-based therapies show potential benefits for treating alopecia, particularly in improving hair density and thickness, and are generally well tolerated with mild and transient adverse events. This systematic review included 7 clinical studies with 323 participants, revealing promising results but with low certainty due to small sample sizes, methodological differences, and incomplete outcome reporting. No serious adverse events were observed. To confirm these findings and ensure safe clinical application, large-scale, well-designed randomized controlled trials with standardized protocols are necessary.