Correspondence on: Exosomes in Trichology: A Literature Review

The correspondence discusses the review by Lee et al. on exosome-based therapies for hair loss conditions like androgenetic alopecia, alopecia areata, and chemotherapy-induced alopecia. It highlights the potential of exosomes due to their regenerative capabilities, influenced by key signaling pathways. However, the field faces challenges in transitioning from biological plausibility to clinical application due to variability in exosome characterization and inconsistent reporting standards. The authors emphasize the need for a standardized framework for exosome therapy, including transparent reporting, standardized characterization, and rigorous safety monitoring, to ensure reproducibility and evidence-based practice. They commend Lee et al. for their valuable synthesis and call for methodological refinement to support the responsible integration of exosome therapeutics into clinical practice.