TLDR PPAR alpha may help in hair growth and could be a target for treatment.
The study investigated the expression of PPAR alpha, delta, and gamma in human hair follicles and found that these receptors were present in both dermal and epithelial cells. It also examined the effect of clofibrate, a PPAR alpha ligand, on hair follicle survival in culture, noting a beneficial effect within a specific concentration range. This suggested that PPAR alpha could play a significant role in regulating hair growth.
111 citations
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April 2000 in “British journal of dermatology/British journal of dermatology, Supplement” Thyroid hormone receptor β1 is found in human hair follicles and helps them survive.
34 citations
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September 1997 in “Acta Dermato Venereologica” RXR agonists may promote hair growth in humans.
47 citations
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24 citations
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27 citations
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55 citations
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May 1985 in “Archives of Dermatology” Calcitriol-resistant rickets is an inherited disorder that affects hair growth and causes hair loss.
