Treatment of Idiopathic Facial Hirsutism with Medroxyprogesterone Acetate Iontophoresis

The study conducted at Military Hospital Rawalpindi over 2 years involved 30 women aged 18-30 with idiopathic facial hirsutism. It evaluated the safety and efficacy of medroxyprogesterone acetate (MPA) administered via iontophoresis. Participants received 1 ml of a 7.5% aqueous MPA solution applied twice weekly for 16 weeks. The treatment targeted the cheeks, with the chin as a control. Results showed a significant reduction in hair length and growth rate without affecting serum androgen levels or causing significant side effects. The study concluded that MPA iontophoresis was a safe, effective, and well-tolerated treatment for idiopathic facial hirsutism.