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GlossaryMedroxyprogesterone Acetate

synthetic hormone used in contraceptives and hormone therapy

Medroxyprogesterone Acetate (MPA) is a synthetic form of the hormone progesterone, commonly used in hormonal contraceptives like Depo-Provera and in hormone replacement therapy. It works by preventing ovulation, thickening cervical mucus to block sperm, and altering the uterine lining to prevent pregnancy. Additionally, MPA is used to treat conditions like endometriosis and abnormal uterine bleeding.

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Research

5 / 340 results

research Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective

123 citations , June 2006 in “Journal of Neurobiology”

Progesterone protects brain cells, but Provera does not.

research Clinical and metabolic effects of medroxyprogesterone acetate and ethinyl estradiol plus drospirenone in women with polycystic ovary syndrome

35 citations , July 2008 in “International Journal of Gynecology & Obstetrics”

MPA improved hormonal imbalances and acne in women with PCOS without affecting metabolism.

research Treatment of alopecia X with medroxyprogesterone acetate

10 citations , September 2013 in “Veterinary dermatology”

Medroxyprogesterone injections caused hair regrowth in some dogs with alopecia X.

research Medroxyprogesterone acetate therapy in hirsutism

7 citations , August 1985 in “British journal of dermatology/British journal of dermatology, Supplement”

Medroxyprogesterone acetate injections are more effective than topical ointment in treating excessive hair growth in women.

research Comparison of resumption of ovulation after cessation of oral contraceptives and medroxyprogesterone acetate in women with polycystic ovary syndrome

1 citations , February 2024 in “Gynecological Endocrinology”

Medroxyprogesterone acetate is as effective as oral contraceptives for resuming ovulation in women with PCOS.

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Community Join

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community Starting Propecia with pre-existing erecticle dysfunction

in Finasteride 5 upvotes 9 years ago

A 19-year-old with diffuse hair thinning and erectile dysfunction is considering starting Propecia (finasteride) while already using a minoxidil solution with anti-androgens. Concerns are raised about the psychological nature of erectile dysfunction and the potential systemic effects of anti-androgens, with suggestions to address porn addiction and consult a doctor about hormone therapy.

community The lowest cyproterone dose to stop mpb

in Treatment 4 upvotes 2 years ago

The conversation discusses using cyproterone acetate at 12.5 mg to manage hair loss, with concerns about its effects on testosterone and potential health issues. Other treatments mentioned include finasteride, dutasteride, minoxidil, and RU58841, with varying experiences and outcomes.

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