Feminizing Adrenocortical Carcinoma Without Gynecomastia

    July 2017 in “ Oman medical journal ”
    Farida Chentli, F. Chabour, Djafer Bouchibane, Nouria Nouar
    TLDR A man with a rare adrenal cancer showed unusual symptoms and died four months after diagnosis.
    The document described a rare case of feminizing adrenocortical carcinoma in a 44-year-old man who presented with abdominal pain and a large retroperitoneal tumor with numerous metastases. Despite high levels of estrogen and other adrenal hormones, the patient did not exhibit gynecomastia, which is typically a major symptom. The absence of gynecomastia was hypothesized to be due to resistance of breast tissue to estradiol. The patient underwent surgery and chemotherapy but unfortunately died four months after diagnosis. The prognosis for such tumors is generally poor, especially when metastases are present at diagnosis.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 101 results

      community (MTF 35) 20 Months Feminizing HRT

      in Transgender  18 upvotes 1 week ago
      A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

      community Transplant Candidate? (26, Male)

      in Transplants  39 upvotes 1 month ago
      A 26-year-old male considering a hair transplant is using topical finasteride and minoxidil, planning to start feminizing hormone replacement therapy (HRT) with estrogen and spironolactone. Many suggest waiting to see the effects of HRT, which may significantly regrow hair, before deciding on a transplant, and recommend adding microneedling and possibly switching to oral treatments for better results.

      community (MTF 35) Results of 18 Months of HRT

      in Transgender  772 upvotes 2 months ago
      A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

      community My Hair loss/regrowth Journey Since 2017

      in Progress Pictures  9 upvotes 1 year ago
      The user shared their hair regrowth journey since 2017, using treatments like finasteride, minoxidil, dutasteride, RU58841, microneedling, and later feminizing HRT. Significant progress was noted after starting HRT, with continued improvement in hair texture and regrowth.

    Related Research

    1 / 1 results