Case Series of Frontal Fibrosing Alopecia and Fibrosing Alopecia in a Pattern Distribution: Is There a Familial Correlation?

January 2023 in “ Skin Appendage Disorders ”

Maria Fernanda Reis Gavazzoni Dias, Amanda Lofeu Cury, Enoï Aparecida Guedes Vilar, Patricia Guimarães Peixoto, Chloe Ekelem

TLDR Frontal fibrosing alopecia may run in families.

The document discussed cases of frontal fibrosing alopecia and fibrosing alopecia in a pattern distribution, highlighting a possible familial correlation. It suggested that there might have been a benefit in conducting systematic scalp examinations on all first-degree relatives of patients with pattern cicatricial alopecia, as evidenced by the disease association observed between mothers and daughters.

View this study on pmc.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Research cited in this study

11 / 11 results

research Familial Frontal Fibrosing Alopecia in Two Male Families

6 citations , June 2019 in “International Journal of Dermatology”

Frontal fibrosing alopecia has occurred in two related male families.

research Fibrosing Alopecia in a Pattern Distribution in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis

13 citations , January 2019 in “Skin appendage disorders”

FAPD is a possible diagnosis for hair loss in patients of color and requires multiple evaluations for accurate diagnosis.

research Familial Frontal Fibrosing Alopecia: A Cross-Sectional Study of 20 Cases from Nine Families

8 citations , November 2018 in “Australasian Journal of Dermatology”

Frontal fibrosing alopecia in families shows similar signs to individual cases and may have a genetic link.

research Case Report of Connubial Frontal Fibrosing Alopecia

6 citations , January 2018 in “International Journal of Trichology”

A married couple both developed a rare type of hair loss, possibly due to shared environmental factors.

research Case Series of Familial Frontal Fibrosing Alopecia and a Review of the Literature

33 citations , January 2015 in “Journal of Cosmetic Dermatology”

Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.

research Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus: Is There a Link?

86 citations , July 2012 in “British journal of dermatology/British journal of dermatology, Supplement”

There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.

research Fibrosing Alopecia in a Pattern Distribution

16 citations , February 2010 in “Journal of the European Academy of Dermatology and Venereology”

Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.

research Female Pattern Hair Loss and Its Relationship to Permanent/Cicatricial Alopecia: A New Perspective

73 citations , November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Some women with common hair loss may develop permanent hair loss.

research Fibrosing Alopecia in a Pattern Distribution Localized on Androgenetic Alopecia Areas and Unaffected Scalp

9 citations , November 2004 in “SKINmed Dermatology for the Clinician”

A man with hair loss developed a condition causing scarring and inflammation in both bald and non-bald areas of his scalp.

research Fibrosing Alopecia in a Pattern Distribution

158 citations , February 2000 in “Archives of dermatology”

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

research Postmenopausal Frontal Fibrosing Alopecia: Scarring Alopecia in a Pattern Distribution

332 citations , June 1994 in “Archives of Dermatology”

Postmenopausal frontal fibrosing alopecia may be a unique condition linked to postmenopausal changes.

Related Research

7 / 7 results

Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

research The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis

41 citations , December 2008 in “International Journal of Dermatology”

South Korean women with hair loss have lower hair density and thickness compared to healthy women.

research Hair Diseases

28 citations , September 1998 in “Medical Clinics of North America”

Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.

research Androgenetic Alopecia, Trichotrophic Substances, and Histologic Studies of the Human Scalp

5 citations , October 1988 in “Clinics in Dermatology”

Minoxidil promotes hair growth but exact mechanism is unknown.

Case Series of Frontal Fibrosing Alopecia and Fibrosing Alopecia in a Pattern Distribution: Is There a Familial Correlation?

Research cited in this study

research Familial Frontal Fibrosing Alopecia in Two Male Families

research Fibrosing Alopecia in a Pattern Distribution in 16 African-Descent and Hispanic Female Patients: A Challenging Diagnosis

research Familial Frontal Fibrosing Alopecia: A Cross-Sectional Study of 20 Cases from Nine Families

research Case Report of Connubial Frontal Fibrosing Alopecia

research Case Series of Familial Frontal Fibrosing Alopecia and a Review of the Literature

research Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus: Is There a Link?

research Fibrosing Alopecia in a Pattern Distribution

research Female Pattern Hair Loss and Its Relationship to Permanent/Cicatricial Alopecia: A New Perspective

research Fibrosing Alopecia in a Pattern Distribution Localized on Androgenetic Alopecia Areas and Unaffected Scalp

research Fibrosing Alopecia in a Pattern Distribution

research Postmenopausal Frontal Fibrosing Alopecia: Scarring Alopecia in a Pattern Distribution

Related Research

research Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil

research Safety and Efficacy of Trimax-360 Serum in Healthy Adult Subjects with Mild to Moderate Alopecia of the Scalp

research Significant Relationship Between Temporal Hair Loss and Other Scalp Areas in Female Pattern Hair Loss

research Break Dancing: A New Risk Factor for Scarring Hair Loss

research The Changing Patterns of Hair Density and Thickness in South Korean Women with Hair Loss: Clinical Office-Based Phototrichogram Analysis

research Hair Diseases

research Androgenetic Alopecia, Trichotrophic Substances, and Histologic Studies of the Human Scalp