Treatment of Frontal Fibrosing Alopecia in Black Patients: A Systematic Review

April 2023 in “ Cutis ”

Josephine Hai

frontal fibrosing alopecia FFA skin of color treatment modalities

TLDR More inclusive research is needed to effectively treat frontal fibrosing alopecia in Black patients.

This systematic review addresses the treatment of frontal fibrosing alopecia (FFA) in Black patients, highlighting the underrepresentation of patients with skin of color in clinical trials and scientific literature. The review evaluates clinical evidence on the efficacy of various treatment modalities for FFA in this demographic. It emphasizes the need for more inclusive research to better understand and manage FFA in patients with skin of color, as current data is limited and often not representative of this group.

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research Frontal Fibrosing Alopecia: A Review of Disease Pathogenesis

2 citations , July 2022 in “Frontiers in Medicine”

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

research Evaluating the Combined Efficacy of Oral Isotretinoin and Topical Tacrolimus Versus Oral Finasteride and Topical Tacrolimus in Frontal Fibrosing Alopecia: A Randomized Controlled Trial

July 2022 in “Journal of Cosmetic Dermatology”

Isotretinoin with tacrolimus may be more effective short-term for treating frontal fibrosing alopecia than finasteride with tacrolimus.

Clinical Characteristics, Trichoscopy, Histopathology, and Treatment Outcomes of Frontal Fibrosing Alopecia in an Asian Population: A Retro-Prospective Cohort Study

research Clinical Characteristics, Trichoscopy, Histopathology, and Treatment Outcomes of Frontal Fibrosing Alopecia in an Asian Population: A Retro-Prospective Cohort Study

9 citations , July 2020 in “Journal of Dermatology”

Asian patients with Frontal Fibrosing Alopecia often lose eyebrow hair and respond well to combined antiandrogen or antimalarial and topical treatments.

research Frontal Fibrosing Alopecia Presenting as Androgenetic Alopecia in an African American Woman

June 2020 in “Journal of Drugs in Dermatology”

Frontal fibrosing alopecia can be misdiagnosed as androgenetic alopecia in African American women.

research Frontal Fibrosing Alopecia: A Case Series of 65 Patients Seen in a Single Italian Centre

23 citations , November 2018 in “Journal of the European Academy of Dermatology and Venereology”

The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.

Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center

research Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center

17 citations , November 2018 in “Dermatology”

Most patients with frontal fibrosing alopecia had facial bumps, with Hispanic/Latino and premenopausal women being more affected, suggesting a more severe condition.

research Frontal Fibrosing Alopecia: Review of Recent Case Reports and Case Series in PubMed

9 citations , August 2018 in “Journal der Deutschen Dermatologischen Gesellschaft”

Most patients with frontal fibrosing alopecia are middle-aged women, often have thyroid disease, and some treatments can help stabilize the condition.

research Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus: Diagnosis and Therapeutic Challenge

16 citations , January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

Managing frontal fibrosing alopecia and lichen planus pigmentosus is challenging due to resistant hair loss and skin discoloration.

research Frontal Fibrosing Alopecia in Association with Sjögren's Syndrome: More Than a Simple Coincidence

12 citations , October 2016 in “Anais Brasileiros de Dermatologia”

Frontal Fibrosing Alopecia may be linked to autoimmune diseases like Sjögren's syndrome.

research Clinical and Dermoscopic Features of Lichen Planus Pigmentosus in 37 Patients with Frontal Fibrosing Alopecia

62 citations , May 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

research Frontal Fibrosing Alopecia in an African Man

13 citations , August 2013 in “International Journal of Dermatology”

Frontal fibrosing alopecia can affect African men and may be underdiagnosed.

research Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus: Is There a Link?

86 citations , July 2012 in “British journal of dermatology/British journal of dermatology, Supplement”

There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.

research Frontal Fibrosing Alopecia: A Review of 60 Cases

166 citations , April 2012 in “Journal of The American Academy of Dermatology”

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

research Frontal Fibrosing Alopecia in Postmenopausal Women

179 citations , December 2004 in “Journal of The American Academy of Dermatology”

Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.

research Postmenopausal Frontal Fibrosing Alopecia

57 citations , January 2003 in “Clinical and experimental dermatology”

Postmenopausal frontal fibrosing alopecia is a type of hair loss in postmenopausal women that may stop on its own but has no effective treatment.

research Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris

329 citations , January 1997 in “Journal of the American Academy of Dermatology”

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

research Postmenopausal Frontal Fibrosing Alopecia: Scarring Alopecia in a Pattern Distribution

332 citations , June 1994 in “Archives of Dermatology”

Postmenopausal frontal fibrosing alopecia may be a unique condition linked to postmenopausal changes.