A Comprehensive Genome-Wide Analysis for Signatures of Selection in Goat (Genus Capra) Revealed New Candidate Genes for Environmental Adaptation and Productive Traits

    October 2025 in “ BMC Genomics
    Stefano Pallotti, Angie Fernanda Rodriguez Garcia, Giovanni Deiana, Marco Antonini, Junwen Zhou, Haizhou Sun, C. Renieri, Valerio Napolioni
    TLDR Goat genes show adaptation to environments and traits like body development, with differences among cashmere, feral, and milk-producing goats.
    This study conducted a comprehensive genome-wide analysis using 194 whole-genome sequencing data sets from various goat populations to identify genetic signatures of selection related to environmental adaptation and productive traits. It found common selection signals in genes associated with body development and environmental adaptation, with distinct genetic clusters among cashmere, feral, and milk-producing goats. Cashmere goats showed high levels of inbreeding and selection for environmental adaptation, particularly in harsh environments, while milk-producing breeds exhibited significant selection for immune response genes. The findings highlight the influence of natural and artificial selection on the goat genome, providing insights for future livestock production and conservation strategies.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results